Article

Isolierung von Bordetella-Phagen aus Bakterienstämen der Impfstoffproduktion†

  1. S. Mebel1,
  2. S. Rustenbach1,
  3. I. A. Lapaeva2

Article first published online: 2 FEB 2004

DOI: 10.1002/abio.370050403

Issue

Acta Biotechnologica

Acta Biotechnologica

Volume 5, Issue 4, pages 329–332, 1985

Additional Information

How to Cite

Mebel, S., Rustenbach, S. and Lapaeva, I. A. (1985), Isolierung von Bordetella-Phagen aus Bakterienstämen der Impfstoffproduktion. Acta Biotechnol., 5: 329–332. doi: 10.1002/abio.370050403

Author Information

  1. 1

    Staatliches Institut für Immunpraäparate und Nährmedien DDR-1120 Berlin, Klement-Gottwald-Allee 317–321

  2. 2

    Akademie der Medizinisches Wissenschaften der UdSSR Gamaleya-Institut für Epidemiologie und Mikrobiologie Moskau, UdSSR

  1. †

    Vortrag auf dem Leipziger Biotechnologiesymposium 1984, 10.–14. 9. 1984

Publication History

  1. Issue published online: 2 FEB 2004
  2. Article first published online: 2 FEB 2004
  3. Manuscript Received: 20 NOV 1984

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Abstract

It has been demonstrated that strains of Bordetella pertussis used for vaccine production contain temperate phages. It can be conducted from many experiments performed in our laboratory. that 10–100 phages per 1010 bacteria are released. However, the production of bacterial mass is not markedly influenced by lysogeny.

Strains of Bordetella bronchiseptica used for production of vaccine against Rhinitis atrophicans of pigs have temperate phages too. These phages may cause a complete lysis during a submerse cultivation.

The phages of Bordetella pertussis and Bordetella bronchiseptica can be propagted on Bordetella parapertussis.

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