Missing correlation of retinal vessel diameter with high-altitude headache
Article first published online: 19 NOV 2013
© 2013 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Annals of Clinical and Translational Neurology
Volume 1, Issue 1, pages 59–63, January 2014
How to Cite
Willmann, G., Fischer, M. D., Schommer, K., Bärtsch, P., Gekeler, F. and Schatz, A. (2014), Missing correlation of retinal vessel diameter with high-altitude headache. Annals of Clinical and Translational Neurology, 1: 59–63. doi: 10.1002/acn3.18
- Issue published online: 22 JAN 2014
- Article first published online: 19 NOV 2013
- Manuscript Accepted: 14 OCT 2013
- Manuscript Revised: 12 OCT 2013
- Manuscript Received: 3 SEP 2013
- Wilderness Medical Society (WMS)
The most common altitude-related symptom, high-altitude headache (HAH), has recently been suggested to originate from restricted cerebral venous drainage in the presence of increased inflow caused by hypoxia. In support of this novel hypothesis, retinal venous distension was shown to correlate with the degree of HAH. We quantified for the first time retinal vessel diameter changes at 4559 m using infrared fundus images obtained from a state of the art Spectralis™ HRA+OCT with a semiautomatic VesselMap 1® software. High-altitude exposure resulted in altered arterial and venous diameter changes at high altitude, however, independent of headache burden.