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acn319-sup-0001-FigS1.tifimage/tif6018KFigure S1. Hemorrhagic transformation. To perform a semi-quantitative assessment of the incidence of hemorrhagic transformation, we developed a grading system based on the following criteria: Grade 0, no hemorrhage; Grade 1, single small hemorrhage; Grade 2, a single large, or multiple small hemorrhages (arrowheads). Boxes, median, and interquartile range; whiskers, min–max; +, mean. Mann–Whitney or Kruskal–Wallis test.

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