Altered cortical activation from the hand after facial botulinum toxin treatment
Article first published online: 25 NOV 2013
© 2013 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.
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Annals of Clinical and Translational Neurology
Volume 1, Issue 1, pages 64–68, January 2014
How to Cite
Haenzi, S., Stefanics, G., Lanaras, T., Calcagni, M. and Ghosh, A. (2014), Altered cortical activation from the hand after facial botulinum toxin treatment. Annals of Clinical and Translational Neurology, 1: 64–68. doi: 10.1002/acn3.21
- Issue published online: 22 JAN 2014
- Article first published online: 25 NOV 2013
- Manuscript Accepted: 25 OCT 2013
- Manuscript Revised: 23 OCT 2013
- Manuscript Received: 13 SEP 2013
- Branco Weiss Fellowship
- OPO-Stiftung Zurich
Plastic interactions between face and hand cortical tactile circuits occur after severe injuries that affect the hand such as in amputation or spinal cord injury. However, whether loss of facial movements alters the cortical circuits involved in processing tactile inputs from the hand remains unknown. In this prospective observational study we used electroencephalography (EEG) to measure cortical activity evoked by tactile stimulation of the hands before and after botulinum toxin-A-induced facial paralysis. We found a reduction in the tactile event-related potentials (ERPs) 6 weeks after the treatment. This suggests that the limited paralysis of facial muscles induced during cosmetic interventions designed to smooth lines and wrinkles on the face is sufficient to alter the cortical processing of tactile inputs from the hand.