Clinicopathologic Conference
You have free access to this content
A woman with severe lupus nephritis and difficult to control diabetes mellitus
Article first published online: 30 MAR 2011
DOI: 10.1002/acr.20403
Copyright © 2011 by the American College of Rheumatology
Additional Information
How to Cite
Buhaescu, I., Rhee, S., York, M. R., McDonnell, M. and Merkel, P. A. (2011), A woman with severe lupus nephritis and difficult to control diabetes mellitus. Arthritis Care Res, 63: 623–629. doi: 10.1002/acr.20403
Publication History
- Issue published online: 30 MAR 2011
- Article first published online: 30 MAR 2011
- Accepted manuscript online: 15 NOV 2010 11:59AM EST
- Manuscript Accepted: 2 NOV 2010
- Manuscript Received: 25 JUN 2010
REFERENCES
- 1, , . Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther 2002; 96: 23–43.
- 2, . Glucocorticoids and insulin resistance: old hormones, new targets. Clin Sci (Lond) 1999; 96: 513–23.
- 3
- 4, , , , , , et al. Immunosuppressive therapy in lupus nephritis: the Euro-Lupus Nephritis Trial, a randomized trial of low-dose versus high-dose intravenous cyclophosphamide. Arthritis Rheum 2002; 46: 2121–31.
- 5, , , , , , et al. Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis: a randomized, controlled trial. Ann Intern Med 1996; 125: 549–57.
- 6, , . Glucose control in the intensive care unit. Crit Care Med 2009; 37: 1769–76.
- 7, . Insulin resistance: mechanisms, syndromes, and implications. N Engl J Med 1991; 325: 938–48.
- 8, , , , , , et al. Insulin resistance in critically ill patients with acute renal failure. Am J Physiol Renal Physiol 2005; 289: F259–64.
- 9, , , , , , et al. The syndromes of insulin resistance and acanthosis nigricans: insulin-receptor disorders in man. N Engl J Med 1976; 294: 739–45.
- 10
- 11, , , , , . Clinical course of the syndrome of autoantibodies to the insulin receptor (type B insulin resistance): a 28-year perspective. Medicine (Baltimore) 2002; 81: 87–100.
- 12, . Insulin resistance: the clinical spectrum. In: MazzaferiE, editor. Advances in endocrinology and metabolism. Vol. 6. St. Louis: Mosby-Year Book; 1995. p. 193–232.
- 13, for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997; 40: 1725.Direct Link:
- 14, , , , , , et al. Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies. Diabetes 2007; 56: 1712–7.
- 15, , , , , , et al. Plasma adiponectin as a marker of insulin receptor dysfunction: clinical utility in severe insulin resistance. Diabetes Care 2008; 31: 977–9.
- 16, , , . Regression of acanthosis nigricans correlates with disappearance of anti-insulin receptor autoantibodies and achievement of euglycemia in type B insulin resistance syndrome. Metabolism 2007; 56: 670–5.
- 17, , , , , , et al. Treatment of type B insulin resistance: a novel approach to reduce insulin receptor autoantibodies. J Clin Endocrinol Metab 2010; 95: 3641–7.
- 18, , , , , . A patient with type B insulin resistance syndrome, responsive to immune therapy. Nat Clin Pract Endocrinol Metab 2007; 3: 835–40.
- 19, . Treatment of type B insulin resistance with immunoglobulin: novel use of an old therapy [letter]. Med J Aust 2009; 190: 168.
- 20, , , , . HIV protease inhibitors acutely impair glucose-stimulated insulin release. Diabetes 2003; 52: 1695–700.
- 21, , , , , . Autoimmune forms of hypoglycemia. Medicine (Baltimore) 2009; 88: 141–53.
- 22, , , , , , et al. Hypoglycemia associated with antibodies to the insulin receptor. N Engl J Med 1982; 307: 1422–6.
- 23, , , . Effects of autoantibodies to the insulin receptor on isolated adipocytes: studies of insulin binding and insulin action. J Clin Invest 1977; 60: 1094–106.
- 24, . Insulin resistance and hypoglycemia in a patient with systemic lupus erythematosus: description of antiinsulin receptor antibodies that enhance insulin binding and inhibit insulin action. J Clin Endocrinol Metab 1991; 73: 650–7.
- 25, , , , , . The evolving clinical course of patients with insulin receptor autoantibodies: spontaneous remission or receptor proliferation with hypoglycemia. J Clin Endocrinol Metab 1978; 47: 985–95.
- 26, , , , , , et al. Type B insulin resistance syndrome with systemic lupus erythematosus. Clin Nephrol 2010; 73: 157–62.
- 27, , , , . Type B insulin resistance syndrome induced by increased activity of systemic lupus erythematosus in a hemodialysis patient. Clin Nephrol 2008; 69: 130–4.

2151-4658/asset/olbannerleft.gif?v=1&s=75d1dd4933b4687fdb365bb32190b0a4ef453ee7)
2151-4658/asset/olbannerright.gif?v=1&s=a36ba6af41bd9af370864f6461a516746a709d31)
