ClinicalTrials.gov identifier: NCT00124254.
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Rheumatoid Arthritis
Long-term followup for rheumatoid arthritis patients in a multicenter outcomes study of silicone metacarpophalangeal joint arthroplasty†
Article first published online: 27 AUG 2012
DOI: 10.1002/acr.21705
Copyright © 2012 by the American College of Rheumatology
Additional Information
How to Cite
Chung, K. C., Burns, P. B., Kim, H. M., Burke, F. D., Wilgis, E. F. S. and Fox, D. A. (2012), Long-term followup for rheumatoid arthritis patients in a multicenter outcomes study of silicone metacarpophalangeal joint arthroplasty. Arthritis Care Res, 64: 1292–1300. doi: 10.1002/acr.21705
- †
Publication History
- Issue published online: 27 AUG 2012
- Article first published online: 27 AUG 2012
- Accepted manuscript online: 17 APR 2012 11:22AM EST
- Manuscript Accepted: 10 APR 2012
- Manuscript Received: 4 JAN 2012
Funded by
- National Institute of Arthritis and Musculoskeletal and Skin Diseases. Grant Number: R01-AR047328
- Midcareer Investigator Award in Patient-Oriented Research. Grant Number: K24-AR053120
Abstract
Objective
Rheumatoid arthritis (RA) often results in deformities at the metacarpophalangeal (MCP) joints. Patients with severe deformities can be treated by silicone metacarpophalangeal joint arthroplasty (SMPA). The objective of the study is to prospectively compare long-term outcomes for an SMPA surgical and a nonsurgical cohort of RA patients.
Methods
A total of 67 surgical and 95 nonsurgical patients with severe subluxation and/or ulnar drift of the fingers at the MCP joints were recruited from 2004–2008 in this multicenter prospective cohort study. Patients could elect to undergo SMPA or not. Outcomes included the Michigan Hand Outcomes Questionnaire (MHQ), Arthritis Impact Measurement Scales 2 (AIMS2), grip/pinch strength, Jebsen-Taylor Test, ulnar deviation, extensor lag, and arc of motion measurements at the MCP joints.
Results
There was no significant difference in the mean age, race, education, and income at baseline between the 2 groups. Surgical subjects had worse MHQ function and functional measurements at baseline. At 3 years, the mean overall MHQ score and the MHQ function, activities of daily living, aesthetics, and satisfaction scores showed significant improvement in the surgical group compared to the nonsurgical group. Ulnar deviation, extensor lag, and arc of motion in the MCP and proximal interphalangeal joints also improved significantly in the surgical group. No improvement was seen in the mean AIMS2 scores and grip/pinch strength. Complications were minimal with a fracture rate of 9.5%.
Conclusion
RA patients with poor baseline functioning showed long-term improvement in hand function and appearance following treatment with SMPA compared to nonsurgical controls.