• 1
    Finckh A, Choi HK, Wolfe F. Progression of radiographic joint damage in different eras: trends towards milder disease in rheumatoid arthritis are attributable to improved treatment. Ann Rheum Dis 2006; 65: 11927.
  • 2
    Schipper LG, Fransen J, den Broeder AA, Van Riel PL. Time to achieve remission determines time to be in remission. Arthritis Res Ther 2010; 12: R97.
  • 3
    Soubrier M, Lukas C, Sibilia J, Fautrel B, Roux F, Gossec L, et al. Disease activity score-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis: data from the GUEPARD trial and ESPOIR cohort. Ann Rheum Dis 2011; 70: 6115.
  • 4
    Van der Bijl AE, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, ten Wolde S, Han KH, van Krugten MV, et al. Infliximab and methotrexate as induction therapy in patients with early rheumatoid arthritis. Arthritis Rheum 2007; 56: 212934.
  • 5
    Rachapalli SM, Williams R, Walsh DA, Young A, Kiely PD, Choy EH. First-line DMARD choice in early rheumatoid arthritis: do prognostic factors play a role? Rheumatology (Oxford) 2010; 49: 126771.
  • 6
    Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight–joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38: 448.
  • 7
    Van der Heijde DM, van 't Hof MA, van Riel PL, van de Putte L. Disease activity score [letter]. Ann Rheum Dis 1992; 51: 140.
  • 8
    Van Riel PL. Disease activity score in rheumatoid arthritis. 2011. URL:
  • 9
    Leeb BF, Andel I, Sautner J, Nothnagl T, Rintelen B. The DAS28 in rheumatoid arthritis and fibromyalgia patients. Rheumatology (Oxford) 2004; 43: 15047.
  • 10
    Leffler AS, Kosek E, Lerndal T, Nordmark B, Hansson P. Somatosensory perception and function of diffuse noxious inhibitory controls (DNIC) in patients suffering from rheumatoid arthritis. Eur J Pain 2002; 6: 16176.
  • 11
    Dhir V, Lawrence A, Aggarwal A, Misra R. Fibromyalgia is common and adversely affects pain and fatigue perception in North Indian patients with rheumatoid arthritis. J Rheumatol 2009; 36: 24438.
  • 12
    Ranzolin A, Brenol JC, Bredemeier M, Guarienti J, Rizzatti M, Feldman D, et al. Association of concomitant fibromyalgia with worse Disease Activity Score in 28 joints, Health Assessment Questionnaire, and Short Form 36 scores in patients with rheumatoid arthritis. Arthritis Rheum 2009; 61: 794800.
  • 13
    Wolfe F, Hauser W, Hassett AL, Katz RS, Walitt BT. The development of fibromyalgia. I. Examination of rates and predictors in patients with rheumatoid arthritis (RA). Pain 2011; 152: 2919.
  • 14
    Heiberg T, Kvien TK. Preferences for improved health examined in 1,024 patients with rheumatoid arthritis: pain has highest priority. Arthritis Rheum 2002; 47: 3917.
  • 15
    Odegard S, Finset A, Mowinckel P, Kvien TK, Uhlig T. Pain and psychological health status over a 10-year period in patients with recent onset rheumatoid arthritis. Ann Rheum Dis 2007; 66: 1195201.
  • 16
    Wolfe F, Michaud K. Assessment of pain in rheumatoid arthritis: minimal clinically significant difference, predictors, and the effect of anti-tumor necrosis factor therapy. J Rheumatol 2007; 34: 167483.
  • 17
    Hakkinen A, Kautiainen H, Hannonen P, Ylinen J, Makinen H, Sokka T. Muscle strength, pain, and disease activity explain individual subdimensions of the Health Assessment Questionnaire disability index, especially in women with rheumatoid arthritis. Ann Rheum Dis 2006; 65: 304.
  • 18
    Hagglund KJ, Haley WE, Reveille JD, Alarcon GS. Predicting individual differences in pain and functional impairment among patients with rheumatoid arthritis. Arthritis Rheum 1989; 32: 8518.
  • 19
    Bekkelund SI, Mellgren SI, Proven A, Husby G. Quantified neurological examination with emphasis on motor and sensory functions in patients with rheumatoid arthritis and controls. Br J Rheumatol 1996; 35: 111621.
  • 20
    Hodge MC, Nathan D, Bach TM. Plantar pressure pain thresholds and touch sensitivity in rheumatoid arthritis. Foot Ankle Int 2009; 30: 19.
  • 21
    Garwood W. The Early Rheumatoid Arthritis Network (ERAN). Musculoskeletal Care 2004; 2: 2404.
  • 22
    Young A, Dixey J, Williams P, Prouse P, Cox N, Kiely P, et al. An evaluation of the strengths and weaknesses of a register of newly diagnosed rheumatoid arthritis, 1986-2010. Rheumatology (Oxford) 2010; 50: 17683.
  • 23
    Young A. What have we learnt from early rheumatoid arthritis cohorts? Best Pract Res Clin Rheumatol 2009; 23: 312.
  • 24
    Kiely P, Williams R, Walsh D, Young A. Contemporary patterns of care and disease activity outcome in early rheumatoid arthritis: the ERAN cohort. Rheumatology (Oxford) 2009; 48: 5760.
  • 25
    Kiely P, Walsh D, Williams R, Young A. Outcome in rheumatoid arthritis patients with continued conventional therapy for moderate disease activity: the Early RA Network (ERAN). Rheumatology (Oxford) 2011; 50: 92631.
  • 26
    Zhang W, Bansback N, Boonen A, Young A, Singh A, Anis AH. Validity of the work productivity and activity impairment questionnaire - general health version in patients with rheumatoid arthritis. Arthritis Res Ther 2010; 12: R177.
  • 27
    Bansback N, Zhang W, Walsh D, Kiely P, Williams R, Guh D, et al. Factors associated with absenteeism, presenteeism and activity impairment in patients in the first years of RA. Rheumatology (Oxford) 2012; 51: 37584.
  • 28
    Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 31524.
  • 29
    Ware JE, Snow KK, Kosinski M. SF-36 health survey: manual and interpretation guide. 2nd ed. Lincoln (RI): QualityMetric; 2000.
  • 30
    Fries JF, Spitz P, Kraines RG, Holman HR. Measurement of patient outcome in arthritis. Arthritis Rheum 1980; 23: 13745.
  • 31
    Birrell FN, Hassell AB, Jones PW, Dawes PT. How does the Short Form 36 health questionnaire (SF-36) in rheumatoid arthritis (RA) relate to RA outcome measures and SF-36 population values? A cross-sectional study. Clin Rheumatol 2000; 19: 1959.
  • 32
    Ruta DA, Hurst NP, Kind P, Hunter M, Stubbings A. Measuring health status in British patients with rheumatoid arthritis: reliability, validity and responsiveness of the Short Form 36-item health survey (SF-36). Br J Rheumatol 1998; 37: 42536.
  • 33
    Van Riel PL, Schumacher HR Jr. How does one assess early rheumatoid arthritis in daily clinical practice? Best Pract Res Clin Rheumatol 2001; 15: 6776.
  • 34
    World Health Organization. Global database on body mass index. 2011. URL:
  • 35
    Wiles NJ, Scott DG, Barrett EM, Merry P, Arie E, Gaffney K, et al. Benchmarking: the five year outcome of rheumatoid arthritis assessed using a pain score, the Health Assessment Questionnaire, and the Short Form-36 (SF-36) in a community and a clinic based sample. Ann Rheum Dis 2001; 60: 95661.
  • 36
    Schumacher HR, Pessler F, Chen LX. Diagnosing early rheumatoid arthritis (RA): what are the problems and opportunities? Clin Exp Rheumatol 2003; 21 Suppl: S159.
  • 37
    Forslind K, Hafstrom I, Ahlmen M, Svensson B. Sex: a major predictor of remission in early rheumatoid arthritis? Ann Rheum Dis 2007; 66: 4652.
  • 38
    Edwards RR, Calahan C, Mensing G, Smith M, Haythornthwaite JA. Pain, catastrophizing, and depression in the rheumatic diseases. Nat Rev Rheumatol 2011; 7: 21624.
  • 39
    Salaffi F, Stancati A, Silvestri CA, Ciapetti A, Grassi W. Minimal clinically important changes in chronic musculoskeletal pain intensity measured on a numerical rating scale. Eur J Pain 2004; 8: 28391.