Dr. Riddle has received honoraria (less than $10,000) for his role as Deputy Editor of Physical Therapy.
Clinically Important Body Weight Gain Following Knee Arthroplasty: A Five-Year Comparative Cohort Study
Article first published online: 23 APR 2013
Copyright © 2013 by the American College of Rheumatology
Arthritis Care & Research
Volume 65, Issue 5, pages 669–677, May 2013
How to Cite
Riddle, D. L., Singh, J. A., Harmsen, W. S., Schleck, C. D. and Lewallen, D. G. (2013), Clinically Important Body Weight Gain Following Knee Arthroplasty: A Five-Year Comparative Cohort Study. Arthritis Care Res, 65: 669–677. doi: 10.1002/acr.21880
- Issue published online: 23 APR 2013
- Article first published online: 23 APR 2013
- Accepted manuscript online: 30 NOV 2012 03:53PM EST
- Manuscript Accepted: 5 OCT 2012
- Manuscript Received: 1 MAY 2012
- Virginia Commonwealth University Presidential Research Initiative Program
The impact of knee arthroplasty on body weight has not been fully explored. Clinically important weight gain following knee arthroplasty would pose potentially important health risks.
We used one of the largest US-based knee arthroplasty registries and a population-based control sample from the same geographic region to determine whether knee arthroplasty increases the risk of clinically important weight gain of ≥5% of baseline body weight over a 5-year postoperative period.
Of the persons in the knee arthroplasty sample, 30.0% gained ≥5% of baseline body weight 5 years following surgery as compared to 19.7% of the control sample. The multivariable-adjusted (age, sex, body mass index, education, comorbidity, and presurgical weight change) odds ratio (OR) was 1.6 (95% confidence interval [95% CI] 1.2–2.2) in persons with knee arthroplasty as compared to the control sample. Additional arthroplasty procedures during followup further increased the risk for weight gain (OR 2.1, 95% CI 1.4–3.1) relative to the control sample. Specifically, among patients with knee arthroplasty, younger patients and those who lost greater amounts of weight in the 5-year preoperative period were at greater risk for clinically important weight gain.
Patients who undergo knee arthroplasty are at an increased risk of clinically important weight gain following surgery. The findings potentially have broad implications to multiple members of the health care team. Future research should develop weight loss/maintenance interventions particularly for younger patients who have lost a substantial amount of weight prior to surgery, as they are most at risk for substantial postsurgical weight gain.