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  • 1
    Pietrangelo A. Hereditary hemochromatosis: a new look at an old disease. N Engl J Med 2004; 350: 238397.
  • 2
    Niederau C, Fischer R, Sonnenberg A. Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis. N Engl J Med 1985; 13: 125662.
  • 3
    Crooks CJ, West J, Solaymani-Dodaran M, Card TR. The epidemiology of haemochromatosis: a population-based study. Aliment Pharmacol Thera 2009; 29: 18392.
  • 4
    Schumacher H Jr. Hemochromatosis and arthritis. Arthritis Rheum 1964; 7: 4150.
  • 5
    Beutler E, Felitti V, Koziol J, Ho N. Penetrance of 845G[RIGHTWARDS ARROW] A (C282Y) HFE hereditary haemochromatosis mutation in the USA. Lancet 2002; 19: 2118.
  • 6
    Allen K, Gurrin L, Constantine C. Iron-overload–related disease in HFE hereditary hemochromatosis. N Engl J Med 2008; 358: 22130.
  • 7
    Sahinbegovic E, Dallos T, Aigner E, Axmann R, Manger B, Englbrecht M, et al. Musculoskeletal disease burden of hereditary hemochromatosis. Arthritis Rheum 2010; 62: 37928.
  • 8
    Sahinbegovic E, Dallos T, Aigner E, Axmann R, Engelbrecht M, Schoniger-Hekele M, et al. Hereditary hemochromatosis as a risk factor for joint replacement surgery. Am J Med 2010; 123: 65962.
  • 9
    Richette P, Ottaviani S, Vicaut E, Bardin T. Musculoskeletal complications of hereditary hemochromatosis: a case-control study. J Rheumatol 2010; 37: 214550.
  • 10
    Hanson E, Imperatore G. HFE gene and hereditary hemochromatosis: a HuGE review. Am J Epidemiol 2001; 154: 193206.
  • 11
    Jacobs EM, Hendriks JC, van Deursen CT, Kreeftenberg HG, de Vries RA, Marx JJ, et al. Severity of iron overload of proband determines serum ferritin levels in families with HFE-related hemochromatosis: the HEmochromatosis FAmily Study. J Hepatol 2009; 50: 17483.
  • 12
    Bulaj ZJ, Griffen LM, Jorde LB, Edwards CQ, Kushner JP. Clinical and biochemical abnormalities in people heterozygous for hemochromatosis. N Engl J Med 1996; 335: 1799805.
  • 13
    Carroll GJ. Primary osteoarthritis in the ankle joint is associated with finger metacarpophalangeal osteoarthritis and the H63D mutation in the HFE gene: evidence for a hemochromatosis- like polyarticular osteoarthritis phenotype. J Clin Rheumatol 2006; 12: 10913.
  • 14
    Cauza E, Hanusch-Enserer U, Etemad M, Koller M, Kostner K, Georg P, et al. HFE genotyping demonstrates a significant incidence of hemochromatosis in undifferentiated arthritis. Clin Exp Rheumatol 2005; 23: 712.
  • 15
    Alizadeh BZ, Njajou OT, Hazes JM, Hofman A, Slagboom PE, Pols HA, et al. The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis. Ann Rheum Dis 2007; 66: 143642.
  • 16
    Ross JM, Kowalchuk RM, Shaulinsky J, Ross L, Ryan D, Phatak PD. Association of heterozygous hemochromatosis C282Y gene mutation with hand osteoarthritis. J Rheumatol 2003; 30: 1215.
  • 17
    Carroll GJ, Breidahl WH, Jazayeri J. Confirmation of two major polyarticular osteoarthritis (POA) phenotypes: differentiation on the basis of joint topography. Osteoarthritis Cartilage 2009; 17: 8915.
  • 18
    Loughlin J, Carr A. The common HFE variants C282Y and H63D are not associated with primary OA of the hip or knee. J Rheumatol 2005; 32: 3912.
  • 19
    Rovetta G, Grignolo MC, Buffrini L, Monteforte P. Prevalence of C282Y mutation in patients with rheumatoid arthritis and spondylarthritis. Int J Tissue React 2002; 24: 1059.
  • 20
    Timms A, Sathananthan R, Bradbury L, Athanasou N, Brown M. Genetic testing for haemochromatosis in patients with chondrocalcinosis. Ann Rheum Dis 2002; 61: 7457.
  • 21
    Willis G, Scott D, Jennings B, Smith K. HFE mutations in an inflammatory arthritis population. Rheumatology (Oxford) 2002; 41: 1769.
  • 22
    Li J, Zhu Y, Singal DP. HFE gene mutations in patients with rheumatoid arthritis. J Rheumatol 2000; 27: 20747.
  • 23
    Carroll G. HFE gene mutations are associated with osteoarthritis in the index or middle finger metacarpophalangeal joints. J Rheumatol 2006; 33: 7413.
  • 24
    Carroll G, Sharma G, Upadhyay A, Jazayeri J. Ferritin concentrations in synovial fluid are higher in osteoarthritis patients with HFE gene mutations (C282Y or H63D). Scand J Rheumatol 2010; 39: 41320.
  • 25
    Lunde A, Lundeborg S. The person-number systems of Sweden, Norway, Denmark, and Israel. Vital Health Stat 1980; 84: 159.
  • 26
    Elmberg M. Mortality and co-morbidity among patients with hemochromatosis and their first-degree relatives [dissertation]. Stockholm (Sweden): Karolinska Institutet; 2011.
  • 27
    National Board of Health and Welfare CFE. The Swedish Hospital Discharge Register, 1987–1995. Stockholm (Sweden): Socialstyrelsen; 1997.
  • 28
    Afonso V, Champy R, Mitrovic D, Collin P, Lomri A. Reactive oxygen species and superoxide dismutases: role in joint diseases. Joint Bone Spine 2007; 74: 3249.
  • 29
    Sinigaglia L, Fargion S, Fracanzani AL, Binelli L, Battafarano N, Varenna M, et al. Bone and joint involvement in genetic hemochromatosis: role of cirrhosis and iron overload. J Rheumatol 1997; 24: 180913.
  • 30
    Heiland GR, Aigner E, Dallos T, Sahinbegovic E, Krenn V, Thaler C, et al. Synovial immunopathology in haemochromatosis arthropathy. Ann Rheum Dis 2010; 69: 12149.
  • 31
    Von Kempis J. Arthropathy in hereditary hemochromatosis. Curr Opin Rheumatol 2001; 13: 803.
  • 32
    Bensen WG, Laskin CA, Little HA, Fam AG. Hemochromatotic arthropathy mimicking rheumatoid arthritis: a case with subcutaneous nodules, tenosynovitis, and bursitis. Arthritis Rheum 1978; 21: 8448.
  • 33
    Pawlotsky Y, Le Dantec P, Moirand R, Guggenbuhl P, Jouanolle AM, Catheline M, et al. Elevated parathyroid hormone 44–68 and osteoarticular changes in patients with genetic hemochromatosis. Arthritis Rheum 1999; 42: 799806.
  • 34
    De Valk B, Addicks MA, Gosriwatana I, Lu S, Hider RC, Marx JJ. Non-transferrin-bound iron is present in serum of hereditary haemochromatosis heterozygotes. Eur J Clin Invest 2000; 30: 24851.
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  • 35
    Adams PC, Speechley M. The effect of arthritis on the quality of life in hereditary hemochromatosis. J Rheumatol 1996; 23: 70710.
  • 36
    Bulaj ZJ, Ajioka RS, Phillips JD, LaSalle BA, Jorde LB, Griffen LM, et al. Disease-related conditions in relatives of patients with hemochromatosis. N Engl J Med 2000; 343: 152935.
  • 37
    Faraawi R, Harth M, Kertesz A. Arthritis in hemochromatosis. J Rheumatol 1993; 20: 44852.
  • 38
    Montgomery KD, Williams JR, Sculco TP, DiCarlo E. Clinical and pathologic findings in hemochromatosis hip arthropathy. Clin Orthop Relat Res 1998; 347: 17987.
  • 39
    Valenti L, Fracanzani AL, Rossi V, Rampini C, Pulixi E, Varenna M, et al. The hand arthropathy of hereditary hemochromatosis is strongly associated with iron overload. J Rheumatol 2008; 35: 1538.
  • 40
    Carroll GJ, Breidahl WH, Bulsara MK, Olynyk JK. Hereditary hemochromatosis is characterized by a clinically definable arthropathy that correlates with iron load. Arthritis Rheum 2011; 63: 28694.
  • 41
    Dymock IW, Hamilton EB, Laws JW, Williams R. Arthropathy of haemochromatosis: clinical and radiological analysis of 63 patients with iron overload. Ann Rheum Dis 1970; 29: 46976.
  • 42
    Hamilton E, Bomford A, Laws J. The natural history of arthritis in idiopathic haemochromatosis: progression of the clinical and radiological features over ten years. Q J Med 1981; 50: 3219.
  • 43
    Lunn JV, Gallagher PM, Hegarty S, Kaliszer M, Crowe J, Murray P, et al. The role of hereditary hemochromatosis in aseptic loosening following primary total hip arthroplasty. J Orthop Res 2006; 23: 5428.
  • 44
    Carlsson A. Hereditary hemochromatosis: a neglected diagnosis in orthopedics. Acta Orthop 2009; 80: 3714.
  • 45
    Wang Y, Gurrin LC, Wluka AE, Bertalli NA, Osborne NJ, Delatycki MB, et al. HFE C282Y homozygosity is associated with an increased risk of total hip replacement for osteoarthritis. Semin Arthritis Rheum 2012; 41: 8728.
  • 46
    Sherrington CA, Knuiman MW, Divitini ML, Bartholomew HC, Cullen DJ, Olynyk JK. Population-based study of the relationship between mutations in the hemochromatosis (HFE) gene and arthritis. J Gastroenterol Hepatol 2006; 21: 5958.
  • 47
    Nelson RL, Persky V, Davis F, Becker E. Risk of disease in siblings of patients with hereditary hemochromatosis. Digestion 2001; 64: 1204.
  • 48
    Elmberg M, Hultcrantz R, Ekbom A, Brandt L, Olsson S, Olsson R, et al. Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives. Gastroenterology 2003; 125: 173341.
  • 49
    Elmberg M, Hultcrantz R, Ebrahim F, Olsson S, Lindgren S, Loof L, et al. Increased mortality risk in patients with phenotypic hereditary hemochromatosis but not in their first-degree relatives. Gastroenterology 2009; 137: 13019.
  • 50
    Baecklund E, Iliadou A, Askling J, Ekbom A, Backlin C, Granath F, et al. Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis. Arthritis Rheum 2006; 54: 692701.