Presented in part at the 75th Annual Scientific Meeting of the American College of Rheumatology, Chicago, IL, November 2011.
Lack of Achievement of a Full Score on the Childhood Myositis Assessment Scale by Healthy Four-Year-Olds and Those Recovering From Juvenile Dermatomyositis†
Article first published online: 24 SEP 2013
Copyright © 2013 by the American College of Rheumatology
Arthritis Care & Research
Volume 65, Issue 10, pages 1697–1701, October 2013
How to Cite
Quiñones, R., Morgan, G. A., Amoruso, M., Field, R., Huang, C.-C. and Pachman, L. M. (2013), Lack of Achievement of a Full Score on the Childhood Myositis Assessment Scale by Healthy Four-Year-Olds and Those Recovering From Juvenile Dermatomyositis. Arthritis Care Res, 65: 1697–1701. doi: 10.1002/acr.22041
- Issue published online: 24 SEP 2013
- Article first published online: 24 SEP 2013
- Accepted manuscript online: 10 MAY 2013 02:31PM EST
- Manuscript Accepted: 17 APR 2013
- Manuscript Received: 7 SEP 2012
- Cure JM Foundation
- Macy's Miracle
To test 4-year-olds, using 14 maneuvers of the Childhood Myositis Assessment Scale (CMAS), comparing healthy children with those with juvenile dermatomyositis (DM).
Healthy 4-year-olds (n = 28) completed the CMAS. Their scores were compared with children with juvenile DM (n = 18) who had a muscle Disease Activity Score (DAS-M) of 0.
The healthy children achieved a mean ± SD CMAS score of 46.6 ± 2.3 (interquartile range 46–47). There were no significant differences between boys and girls, and the scores were not significantly associated with height or weight. The greatest variation involved items that assessed endurance. Item 1, neck raise, yielded a mean ± SD score of 28.2 ± 19.3 seconds, with a mean ± SD CMAS score of 2.5 ± 0.9 (maximum score 5). Item 3, leg lift, yielded a mean ± SD score of 55.5 ± 37.3 seconds, with a mean ± SD CMAS score of 3.1 ± 1.1 (maximum score 5). Item 5, sit-ups maneuver, yielded a mean ± SD score of 5.3 ± 1.1 sit-ups. Almost identical data were obtained for the 18 treated children with juvenile DM who had normal strength on the DAS-M.
Healthy children ages 4 years do not achieve the total CMAS score of 52 attained by older children. Both boys and girls were remarkably consistent, with a mean CMAS score of 46.6. Children ages 4 years with juvenile DM with a DAS-M of 0 also achieved a CMAS score of 46.6. We conclude that half of 4-year-old children achieve a mean CMAS score of 46 or 47, not a total CMAS score of 52, suggesting that weakness may be overdiagnosed in 4-year-olds with an inflammatory myopathy.