Both authors contributed equally to this work
In Vitro Biocompatibility of n-Type and Undoped Silicon Nanowires†
Article first published online: 23 NOV 2010
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Advanced Engineering Materials
Volume 13, Issue 1-2, pages B3–B9, February, 2011
How to Cite
Garipcan, B., Odabas, S., Demirel, G., Burger, J., Nonnenmann, S. S., Coster, M. T., Gallo, E. M., Nabet, B., Spanier, J. E. and Piskin, E. (2011), In Vitro Biocompatibility of n-Type and Undoped Silicon Nanowires. Adv. Eng. Mater., 13: B3–B9. doi: 10.1002/adem.200980045
Gokhan Demirel was supported as a post-doctoral fellow by The Scientific and Technological Research Council of Turkey (TUBITAK). Prof. Dr. Erhan Piskin was supported by Turkish Academy of Sciences (TUBA) as a full member. Jonathan Spanier acknowledges partial support for this work from the US Army Research Office (ARO) Materials Sciences Division, under YIP Award No. W911NF-04-1-0308 and from the Defense University Research Instrumentation Program (DURIP) Award No. W911NF-06-1-0127, and from the Department of Health of the Commonwealth of Pennsylvania.
- Issue published online: 26 JAN 2011
- Article first published online: 23 NOV 2010
- Manuscript Revised: 23 JUL 2010
- Manuscript Received: 5 NOV 2009
- silicon nanocomposite
The biocompatibility of undoped and n-type silicon nanowires (SiNWs), synthesized by metal-catalyzed chemical vapor deposition, was investigated in vitro, and compared with that for SiO2-coated silicon wafers. In cell interaction studies, L929 mouse fibroblast cells were used, in which MTT assay, AO/PI dye staining, cell proliferation/growth, and changes in cell adhesion/morphology on the surfaces were applied and investigated. Heamocompatibility of these materials were also tested. No significant cytotoxic effects were observed for either the undoped or for the n-type phosphorus-doped SiNWs. The cells on the nanowires exhibit high viability, normal nuclear, and morphological structure. They have shown no considerable negative blood response with respect to the control.