Acknowledgements: This study was funded by Heraeus Kulzer GmbH, Germany.
Biomimetic Mineralization: Effects on Human Enamel In Vivo†
Article first published online: 7 OCT 2010
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Advanced Engineering Materials
Special Issue: 1st Sino-German Symposium on Advanced Biomedical Nanostructures
Volume 12, Issue 9, pages B571–B576, September, 2010
How to Cite
Guentsch, A., Busch, S., Seidler, K., Kraft, U., Nietzsche, S., Preshaw, P. M., Chromik, J. N., Glockmann, E., Jandt, K. D. and Sigusch, B. W. (2010), Biomimetic Mineralization: Effects on Human Enamel In Vivo. Adv. Eng. Mater., 12: B571–B576. doi: 10.1002/adem.201080008
- Issue published online: 27 OCT 2010
- Article first published online: 7 OCT 2010
- Manuscript Revised: 26 FEB 2010
- Manuscript Received: 14 JAN 2010
Dental caries, and tooth surface loss by erosion, abrasion, and attrition lead to irreversible loss of dental tissue. Enamel is a highly mineralized acellular tissue and cannot be regenerated after tooth eruption. Currently available restorative materials, such as composites, replace lost tooth structure and improve function and aesthetics. However, these materials have no structural similarities to natural tooth structure. The efficacy of an experimental biomimetic mineralization-kit was tested in a clinical pilot study in patients with hypersensitive teeth. Enamel defects were effectively treated by addition of a fluoroapatite layer.