Metal Foam – Bone Cement Composites: Mechanical and Biological Properties and Perspectives for Bone Implant Design


  • We thank Ulrike Porstendörfer (InnoTERE, Dresden, Germany) for technical assistance and the University Hospital Carl Gustav Carus Dresden at the Technische Universität Dresden (Germany) for providing hMSC. We like to thank the Federal Ministry of Education and Research (BMBF, Berlin, Germany) and the project coordinator PTJ (Jülich, Germany) for the financial support (funding number 03WKBH3).


Several approaches for the development of highly porous metal structures with intended medical application have been published in recent years. Considering both the demands of sufficient mechanical strength for loaded bone implants as well as prevention of the stress shielding phenomena, open-cell metal foams are reinforced with strong but resorbable mineral bone cement. Titanium- and iron-based composites with highly prolonged stress resilence and favorable cytoxicity are achieved. Resorption of mineral phase gradually decreases the implant stability while concurrently raising the bone regeneration through mechanical stimulation. Furthermore, iron-based composites are intended to be resorbed and corrode consecutively. Thus, a temporary bone implant can be obtained.