Research Article

Application of a Bioactive Coating on Resorbable, Neodymium Containing Magnesium Alloys, and Analyses of their Effects on the In Vitro Degradation Behavior in a Simulated Body Fluid†

  1. Jan-Marten Seitz1,*,
  2. Ulrike Bormann1,
  3. Kelly Collier2,
  4. Eric Wulf1,
  5. Rainer Eifler1,
  6. Friedrich Wilhelm Bach1

Article first published online: 10 FEB 2012

DOI: 10.1002/adem.201180078

Additional Information

How to Cite

Seitz, J.-M., Bormann, U., Collier, K., Wulf, E., Eifler, R. and Bach, F. W. (2012), Application of a Bioactive Coating on Resorbable, Neodymium Containing Magnesium Alloys, and Analyses of their Effects on the In Vitro Degradation Behavior in a Simulated Body Fluid. Adv. Eng. Mater.. doi: 10.1002/adem.201180078

Author Information

  1. 1

    Institute of Materials Science, Leibniz Univerität Hannover, An der Universität 2, 30823 Hannover, Germany

  2. 2

    Department of Materials Science, Carnegie Mellon University, 500 Forbes Avenue, 15213 Pittsburgh, Pennsylvania, USA

*Institute of Materials Science, Leibniz Univerität Hannover, An der Universität 2, 30823 Hannover, Germany Fax: +49 511 762-5245.

  1. †

    All work carried out for this study was done within the Collaborative Research Centre 599 “Sustainable bioresorbable and permanent implants of metallic and ceramic materials” Subproject R1, which was funded by the German Research Foundation (DFG). The authors would like to thank Petra Hoyer, Anja Krabbenhöft, Christoph Hübsch, and Harald Kernbach for their assistance in providing the polarization curve, EDX, FTIR, and three-point bending measurements.

Publication History

  1. Article first published online: 10 FEB 2012
  2. Manuscript Accepted: 5 JAN 2012
  3. Manuscript Received: 1 AUG 2011

Funded by

  • German Research Foundation (DFG)

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Abstract

Whilst bioactive coatings are commonly used as layers for non-resorbable implant materials, such as titanium or steel to improve cell adhesion, this study investigates the application of bioactive SiO2–CaO–P2O5 on resorbable magnesium alloys (Nd2 and LANd442). The bioactive coating was applied to the magnesium alloys by a dip-coating process, where a parameter set of 20 immersions and a 10 s drying time between each immersion generated a reproducible layer with regard to its thickness and homogeneity. In vitro mass loss, strength loss, and pH value measurements were used to determine the coating's effects on the degradation behavior in a simulated body fluid. Here, it could be observed that bioactive layers on magnesium alloys lead to an increased degradation in comparison to specimens in the uncoated states. In addition to this, pitting corrosion was determined for bioactive coated magnesium samples during comparatively early periods of the investigation. Due to the decreased corrosion resistance and induced pitting corrosion of bioactive coated magnesium alloys, it is suggested that one carefully tests if the enhanced cell adhesion, which occurs with bioactive coatings, warrants the increased degradation of magnesium based implant materials.

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