Adv. Eng. Mater. 10/2009
Zhi-Min Dang, Chun-Yan Tian, Jun-Wei Zha, Sheng-Hong Yao, Yu-Juan Xia, Jian-Ying Li, Chang-Yong Shi and Jinbo Bai
Article first published online: 23 OCT 2009 | DOI: 10.1002/adem.200990027
When the BT nanoparticles are also embedded into the polymer, the surface charges of the three-phase (BT-HA)/PVDF nanocomposites would be formed after an electrical field is applied on them because the BT particles can be polarized easily [See Picture (a)]. The surface charges or the static electric field [See Picture (b)] from the surface charges would accelerate the bone regeneration significantly. Therefore, the time for bone-regeneration of the three-phase (BT-HA)/PVDF nanocomposites would be shorten than that of the two-phase HA/PVDF nanocomposites, and the effect on bone regeneration would be much better. Namely, the HA can enhance osteoblast differentiation as well as osteoblast growth while the surface charges from the BT polarization can further encourage those actions of HA in our three-phase (BT-HA)/PVDF nanocomposites with high permittivity [See Picture (c)]. See article by Z.-M. Dang, p. B144.