In vivo Performance of Osteoactivated Cellulose-Based Scaffolds in Bony Critical-Size Defects (pages B89–B97)
Sabine Ponader, Heike Brandt, Eleftherios Vairaktaris, Cornelius von Wilmowsky, Wolfgang Göthel, Rainer Lutz, Karl A. Schlegel, Friedrich W. Neukam, Peter Greil, Frank A. Müller and Emeka Nkenke
Article first published online: 3 AUG 2009 | DOI: 10.1002/adem.200800437
Cellulose-based scaffolds osteoactivated with different sodium silicate coatings (pure and bisphosphonate or strontium enriched respectively) can serve as long-term depots for a slow drug-release. Thus they are a promising and cost-saving alternative to the short-lived drug delivery systems of recombinant bone promoting proteins.