Purification of Nano-Porous Silicon for Biomedical Applications (pages B225–B233)
Svetoslav Koynov, Rui N. Pereira, Ivo Crnolatac, Dmitry Kovalev, Ann Huygens, Vladimir Chirvony, Martin Stutzmann and Peter de Witte
Article first published online: 16 MAR 2011 | DOI: 10.1002/adem.201080091
Photoactive nano-porous silicon particles (np-Si) contain considerable amounts of toxic residua from their fabrication by chemical (electrochemical) etching of silicon. These impurities are hazardous for bio-medical applications of np-Si, such as O2-photosensitization in photodynamic therapy and drug delivery. A purification procedure is developed, capable of reducing the concentration of residual impurities to levels acceptable for bio-medical applications, while preserving a desired biological photo-activity of the particles.