Poly(Ethylene Glycol) Based Hydrogels for Intraocular Applications (pages 1141–1149)
F. Brandl, M. Henke, S. Rothschenk, R. Gschwind, M. Breunig, T. Blunk, J. Tessmar and A. Göpferich
Article first published online: 19 DEC 2007 | DOI: 10.1002/adem.200700221
Hydrogels are attractive materials for biomedical applications due to their versatility and excellent biocompatibility. In this study, the authors report the preparation of poly(ethylene glycol) (PEG) based hydrogels for intraocular applications. Transparent hydrogels were formed in situ upon chemical reaction of these macromers. The cross-linked hydrogels showed no cytotoxic effects and may be used as vitreous substitutes or intraocular drug release systems.