This work was supported by the National Natural Science Foundation of China (No.20206019) and the Trans-Century Training Programme Foundation for the Talents by the Ministry of Education of China.
Positively Thermo-Sensitive Monodisperse Core–Shell Microspheres†
Article first published online: 5 NOV 2003
Copyright © 2003 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Advanced Functional Materials
Volume 13, Issue 11, pages 847–852, November, 2003
How to Cite
Xiao, X.-C., Chu, L.-Y., Chen, W.-M., Wang, S. and Li, Y. (2003), Positively Thermo-Sensitive Monodisperse Core–Shell Microspheres. Adv. Funct. Mater., 13: 847–852. doi: 10.1002/adfm.200304513
- Issue published online: 5 NOV 2003
- Article first published online: 5 NOV 2003
- Manuscript Accepted: 5 SEP 2003
- Manuscript Received: 20 AUG 2003
- Core-shell particles;
- Interpenetrating networks
In this paper, we report on a novel family of monodisperse thermo-sensitive core–shell hydrogel microspheres that is featured with high monodispersity and positively thermo-responsive volume phase transition characteristics with tunable swelling kinetics, i.e., the particle swelling is induced by an increase rather than a decrease in temperature. The microspheres were fabricated in a three-step process. In the first step, monodisperse poly(acrylamide-co-styrene) seeds were prepared by emulsifier-free emulsion polymerization. In the second step, poly(acrylamide) or poly[acrylamide-co-(butyl methacrylate)] shells were fabricated on the microsphere seeds by free radical polymerization. In the third step, the core–shell microspheres with poly- (acrylamide)/poly(acrylic acid) based interpenetrating polymer network (IPN) shells were finished by a method of sequential IPN synthesis. The proposed monodisperse core–shell microspheres provide a new mode of the phase transition behavior for thermo-sensitive “smart” or “intelligent” monodisperse micro-actuators that is highly attractive for targeting drug delivery systems, chemical separations, sensors, and so on.