Scaffolds Based on Biopolymeric Foams


  • The authors acknowledge the University of Rome “La Sapienza” for financial support (Ateneo funds) and Dr. Fiorella Malchiodi-Albedi for providing mouse retina cells.


A new approach for the preparation of hydrophilic and biocompatible porous scaffolds is described. The procedure involves the derivatization of a biopolymer by the introduction of vinylic moieties, formation of a high-internal-phase oil-in-water emulsion, and its subsequent polymerization. The ensuing materials are characterized by a highly porous morphology represented by pores completely interconnected by a plurality of holes. The hydrophilic and biocompatible nature of these materials make them good candidates for application as scaffolds for tissue engineering.