Cover Picture: SERS Aptatags: New Responsive Metallic Nanostructures for Heterogeneous Protein Detection by Surface Enhanced Raman Spectroscopy (Adv. Funct. Mater. 17/2008)

Authors

  • Laura Fabris,

    1. Departments of Chemistry and Biochemistry and Materials Center for Polymers and Organic Solids University of California Santa Barbara, CA 93106 (USA)
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  • Mark Dante,

    1. Departments of Chemistry and Biochemistry and Materials Center for Polymers and Organic Solids University of California Santa Barbara, CA 93106 (USA)
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  • Thuc-Quyen Nguyen,

    1. Departments of Chemistry and Biochemistry and Materials Center for Polymers and Organic Solids University of California Santa Barbara, CA 93106 (USA)
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  • Jeffrey B.-H. Tok,

    1. BioSecurity and NanoSciences Laboratory, Chemistry, Materials and Life Sciences Directorate Lawrence Livermore National Laboratories Livermore, CA 94551 (USA)
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  • Guillermo C. Bazan

    Corresponding author
    1. Departments of Chemistry and Biochemistry and Materials Center for Polymers and Organic Solids University of California Santa Barbara, CA 93106 (USA)
    • Departments of Chemistry and Biochemistry and Materials Center for Polymers and Organic Solids University of California Santa Barbara, CA 93106 (USA).
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Abstract

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On page 2518, Bazan and co-workers describe the design and function of “aptatags” that consist of aptamer-decorated silver nanoparticles brought together by an organic linker. This linkeris strategically located where surface enhancement of Raman signals takes place. The aptamer probes were chosen to selectively bind specific proteins. These structural attributes of aptatags allow the development of a new heterogeneous protein detection method.

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