DNA Detection: Intercalating Dye Harnessed Cationic Conjugated Polymer for Real-Time Naked-Eye Recognition of Double-Stranded DNA in Serum (Adv. Funct. Mater. 9/2009)

Authors

  • Kan-Yi Pu,

    1. Department of Chemical and Biomolecular Engineering National University of Singapore (NUS) Singapore 117576 (Singapore) Fax: (+65) 6779-1936
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  • Bin Liu

    Corresponding author
    1. Department of Chemical and Biomolecular Engineering National University of Singapore (NUS) Singapore 117576 (Singapore) Fax: (+65) 6779-1936
    • Department of Chemical and Biomolecular Engineering National University of Singapore (NUS) Singapore 117576 (Singapore) Fax: (+65) 6779-1936.
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Abstract

original image

On page 1371, Liu Bin and Pu Kan-Yi demonstrate multicolor detection of double-stranded DNA in biological media using an intercalating-dye-harnessed cationic conjugated polymer. As demonstrated in the cover image, the intercalating-dye-harnessed polymer emits blue fluorescence both in the absence and presence of single-stranded DNA in serum-containing solution, while its fluorescence gradually turns from blue to dark yellow with increasing double-stranded DNA concentration.

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