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Keywords:

  • cell adhesion;
  • cellular patterning;
  • microcontact chemistry;
  • self-assembled monolayers;
  • zeolite L

Abstract

Chemically functionalized self-assembled monolayers made by disk-shaped zeolite L nanocrystals are used as models for biocompatible surfaces to study cell-adhesion behavior. Different chemical groups lead to different cellular behavior and fluorescent-molecule-loaded zeolites allow the position of the cells to be determined. Furthermore, a patterned monolayer of asymmetrically functionalized zeolite L obtained by microcontact chemistry is used to grow cells. A spatial recognition of the cells, which proliferate only on the bioactive-molecule-functionalized stripes, is possible.