Micropatterning: Patterned Hydrogels for Controlled Platelet Adhesion from Whole Blood and Plasma (Adv. Funct. Mater. 15/2010)

Authors

  • Tobias Ekblad,

    1. Division of Molecular Physics Department of Physics, Chemistry and Biology Linköping University, SE-581 83 Linköping (Sweden)
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  • Lars Faxälv,

    1. Division of Clinical Chemistry Department of Clinical and Experimental Medicine Linköping University, SE-581 85 Linköping (Sweden)
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  • Olof Andersson,

    1. Division of Molecular Physics Department of Physics, Chemistry and Biology Linköping University, SE-581 83 Linköping (Sweden)
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  • Nanny Wallmark,

    1. Division of Molecular Physics Department of Physics, Chemistry and Biology Linköping University, SE-581 83 Linköping (Sweden)
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  • Andréas Larsson,

    1. Division of Molecular Physics Department of Physics, Chemistry and Biology Linköping University, SE-581 83 Linköping (Sweden)
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  • Tomas L. Lindahl,

    1. Division of Clinical Chemistry Department of Clinical and Experimental Medicine Linköping University, SE-581 85 Linköping (Sweden)
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  • Bo Liedberg

    Corresponding author
    1. Division of Molecular Physics Department of Physics, Chemistry and Biology Linköping University, SE-581 83 Linköping (Sweden)
    • Division of Molecular Physics Department of Physics, Chemistry and Biology Linköping University, SE-581 83 Linköping (Sweden)
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Abstract

original image

Poly(ethylene glycol)-based hydrogel coatings patterned with selected proteins can be utilized to control and study the adhesion of human blood platelets with excellent precision, as presented by B. Liedberg et al. on page 2396. This frontispiece shows how imaging surface plasmon resonance is used in combination with fluorescence microscopy to investigate the platelet adhesion process in undiluted blood plasma.

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