Full Paper
CCVD Synthesis of Carbon-Encapsulated Cobalt Nanoparticles for Biomedical Applications
Article first published online: 15 AUG 2011
DOI: 10.1002/adfm.201100364
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Lukanov, P., Anuganti, V. K., Krupskaya, Y., Galibert, A.-M., Soula, B., Tilmaciu, C., Velders, A. H., Klingeler, R., Büchner, B. and Flahaut, E. (2011), CCVD Synthesis of Carbon-Encapsulated Cobalt Nanoparticles for Biomedical Applications. Adv. Funct. Mater., 21: 3583–3588. doi: 10.1002/adfm.201100364
Publication History
- Issue published online: 20 SEP 2011
- Article first published online: 15 AUG 2011
- Manuscript Revised: 27 MAY 2011
- Manuscript Received: 16 FEB 2011
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Keywords:
- carbon-encapsulated cobalt nanoparticles;
- CCVD;
- magnetic properties;
- hyperthermia;
- magnetic resonance imaging (MRI).
Abstract
Carbon-encapsulated ferromagnetic Cobalt nanoparticles (Co@C) have been synthesized by catalytic chemical vapour deposition (CCVD). The nanoparticles, mainly ranging between 10 and 15 nm, are tightly encapsulated by 2–3 concentric graphitic carbon shells and protected from oxidation. Because of their magnetic properties (saturation magnetization of 106 emu/g and a coercivity HC of 250 Oe), Co@C nanoparticles have been investigated for hyperthermia application. Although the observed values of the specific absorption rate (28.7 W/gCo@C at 30 kA/m and 215.4 W/gCo@C at 70 kA/m) are slightly lower than required in actual hyperthermia therapies, the observed strong heating effect provides a very promising starting point for future clinical application. It is also demonstrated that these nanoparticles can at the same time be used for magnetic resonance imaging (MRI) with an efficiency comparable to commercially available T2 contrast agents.

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