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Chirality-Triggered Protein Adsorption: Chiral Design for Polymeric Biointerface: The Influence of Surface Chirality on Protein Adsorption (Adv. Funct. Mater. 17/2011)

Authors

  • Xing Wang,

    1. Physicalisches Institut, Muenster University Wilhelm-Klemm-Str. 10, D-48149 Muenster, Germany
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  • Hui Gan,

    1. Physicalisches Institut, Muenster University Wilhelm-Klemm-Str. 10, D-48149 Muenster, Germany
    2. Beijing Institute of Transfusion, Medicine Beijing 100850, China
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  • Taolei Sun

    Corresponding author
    1. Physicalisches Institut, Muenster University Wilhelm-Klemm-Str. 10, D-48149 Muenster, Germany
    2. State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China
    • Physicalisches Institut, Muenster University Wilhelm-Klemm-Str. 10, D-48149 Muenster, Germany.
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Abstract

original image

Surface chirality is introduced, for the first time, into the research of protein/surface interactions by Taolei Sun and co-workers on page 3276. Comparing a pair of chiral polymer films based on L(D)-amino acid units, the L film shows signifi cantly stronger interactions with proteins than the corresponding D film. Thermodynamic studies reveal a stereoselective mechanism dominated by hydrophobic interactions.

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