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Biomaterials: Biofunctional Silk/Neuron Interfaces (Adv. Funct. Mater. 9/2012)

Authors

  • Valentina Benfenati,

    Corresponding author
    1. Consiglio Nazionale delle Ricerche (CNR), Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), via Gobetti, 101, 40129, Bologna, Italy
    • Consiglio Nazionale delle Ricerche (CNR), Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), via Gobetti, 101, 40129, Bologna, Italy.
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  • Katja Stahl,

    1. Center for Molecular Biology and Neuroscience, University of Oslo, P.O. Box 1105 Blindern NO-0317 Oslo, Norway
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  • Carolina Gomis-Perez,

    1. Department of Human and General Physiology, University of Bologna, via S. Donato 19/2, 40127, Bologna, Italy
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  • Stefano Toffanin,

    1. Consiglio Nazionale delle Ricerche (CNR), Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), via Gobetti, 101, 40129, Bologna, Italy
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  • Anna Sagnella,

    1. Consiglio Nazionale delle Ricerche (CNR), Istituto per la Sintesi Organica e la Fotoreattività (ISOF), via Gobetti, 101, 40129, Bologna, Italy
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  • Reidun Torp,

    1. Center for Molecular Biology and Neuroscience, University of Oslo, P.O. Box 1105 Blindern NO-0317 Oslo, Norway
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  • David L. Kaplan,

    1. Department for Biomedical Engineering, Tufts University, Medford, MA 02155, USA
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  • Giampiero Ruani,

    1. Consiglio Nazionale delle Ricerche (CNR), Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), via Gobetti, 101, 40129, Bologna, Italy
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  • Fiorenzo G. Omenetto,

    1. Department for Biomedical Engineering, Tufts University, Medford, MA 02155, USA
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  • Roberto Zamboni,

    1. Consiglio Nazionale delle Ricerche (CNR), Istituto per la Sintesi Organica e la Fotoreattività (ISOF), via Gobetti, 101, 40129, Bologna, Italy
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  • Michele Muccini

    Corresponding author
    1. Consiglio Nazionale delle Ricerche (CNR), Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), via Gobetti, 101, 40129, Bologna, Italy
    • Consiglio Nazionale delle Ricerche (CNR), Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), via Gobetti, 101, 40129, Bologna, Italy.
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Abstract

original image

On page 1871 Valentina Benfenati, Michele Muccini, and co-workers demonstrate that silk films act as biofunctional interfaces that support the adherence, neurite outgrowth, and intercellular communication of neurons. Silk films have huge potential for use in electronic devices aimed at stimulating neural network activity and peripheral nerve repair. The image depicts a synaptic process occurring on silk fibroin films from Bombyx mori cocoon.

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