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Keywords:

  • hydrogen peroxide;
  • antioxidant;
  • chemiluminescence;
  • imaging;
  • inflammation
Thumbnail image of graphical abstract

Chemiluminescent micelles contain polyoxalate and fluorophore in the core and are capable of performing a peroxalate chemiluminescence reaction with hydrogen peroxide. Hydrogen peroxide is generated in large amounts during inflammatory responses. As reported by Dongwon Lee and co-workers on page 4038, diffusion of hydrogen peroxide into the interior of chemiluminescent micelles initiates the peroxalate chemiluminescence reaction and subsequent light emission, allowing the detection of inflammatory diseases.