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Keywords:

  • electrospun polymer nanofibers;
  • ethanol dispersion;
  • CD4+ T lymphocyte;
  • cell separation;
  • cell transplantation
Thumbnail image of graphical abstract

Electrospun and alcohol-dispersed polystyrene-poly(styreneco-maleic anhydride) (PS-PSMA) nanofibers, which allow for facile conjugation of antibodies, are used as an innovative cell isolation/enrichment and support/release platform. As reported by Kyung-Mi Lee, Jungbae Kim, and co-workers on page 4448, this work opens up the potential for an innovative immune cell therapy in which specific immune cells are isolated by antibody-conjugated nanofibers and are directly delivered to the target sites under the controlled and sustained release of immune cells via in vivo activation.