Drug Delivery: Templated Assembly of pH-Labile Polymer-Drug Particles for Intracellular Drug Delivery (Adv. Funct. Mater. 22/2012)

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Abstract

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Polymer carriers with finely controlled and responsive properties have received increasing interest for biomedical applications. On page 4718, Frank Caruso and co-workers report a facile and robust approach to prepare pH-labile drug-loaded polymer particles by combining mesoporous silica-templated assembly and polymer-drug conjugates for drug delivery into cancer cells. These particles are a novel and versatile class of stimuli-responsive carriers for controlled drug delivery.

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