Folded bioactive membranes are made in a singlestep process via the self-assembly of multidomain peptides with hyaluronic acid in combination with soft-lithography. As Alvaro Mata and co-workers report on page 430, the hierarchical membrane exhibits well-defined functional nanofibers bearing biomolecular signals and precise post micropatterns. These bioactive membranes have broad potential applications in tissue engineering and regenerative medicine.
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