Drug Delivery: Fabrication of Nanofiber Microarchitectures Localized within Hydrogel Microparticles and Their Application to Protein Delivery and Cell Encapsulation (Adv. Funct. Mater. 5/2013)

Authors

  • Hyun Jong Lee,

    1. Active Polymer Center for Pattern Integration, Department of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, South Korea
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  • Young Ha Park,

    1. Active Polymer Center for Pattern Integration, Department of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, South Korea
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  • Won-Gun Koh

    Corresponding author
    1. Active Polymer Center for Pattern Integration, Department of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, South Korea
    • Active Polymer Center for Pattern Integration, Department of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, South Korea.
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Abstract

original image

On page 591, Won-Gun Koh and co-workers report a simple method to generate well-defined microscopic architectures of electrospun nanofibers and describe their potential applications in biomedical fields. A combination of electrospinning and hydrogel patterning generates microarchitectured nanofibers that are localized within various shapes of hydrogel microparticles. Resultant nanofiber-entrapped hydrogels can be used for sustained release of protein and cell encapsulation

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