Self-Assembly: Reinforcement of Shear Thinning Protein Hydrogels by Responsive Block Copolymer Self-Assembly (Adv. Funct. Mater. 9/2013)

Authors

  • Matthew J. Glassman,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Room 66-556, Cambridge, MA 02139, USA
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  • Jacqueline Chan,

    1. Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA
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  • Bradley D. Olsen

    Corresponding author
    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Room 66-556, Cambridge, MA 02139, USA
    • Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Room 66-556, Cambridge, MA 02139, USA.
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Abstract

original image

Triblock copoylmers with associative protein midblocks and thermoresponsive endblocks form shear thinning hydrogels that can be injected at low temperature. On page 1182, Bradley D. Olsen and co-workers report that when warmed to body temperature, the gel is responsively reinforced as the endblocks self-assemble into a secondary block copolymer network, leading to large increases in modulus and yield stress, and decreased erosion and creep compliance.

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