Biomimetics: Virus-Tethered Magnetic Gold Microspheres with Biomimetic Architectures for Enhanced Immunoassays (Adv. Funct. Mater. 12/2013)

Authors

  • Chang Su Jeon,

    1. Department of Chemistry, College of Natural Science, Seoul National University, Seoul 151-747, Korea
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  • Inseong Hwang,

    Corresponding author
    1. Department of Chemistry, College of Natural Science, Seoul National University, Seoul 151-747, Korea
    • Department of Chemistry, College of Natural Science, Seoul National University, Seoul 151-747, Korea.
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  • Taek Dong Chung

    Corresponding author
    1. Department of Chemistry, College of Natural Science, Seoul National University, Seoul 151-747, Korea
    • Department of Chemistry, College of Natural Science, Seoul National University, Seoul 151-747, Korea.
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Abstract

original image

Inspired by the cellular threadlike structures, virus-decorated gold microspheres with high surface to volume ratios are described by Chang Su Jeon, Inseong Hwang, and Taek Dong Chung on page 1484. The filamentous viral scaffold allows dense modification with antibodies, while the thin gold layer protects non-specific bindings from serum samples, resulting in a significant increase in sensitivity in the bead-based immunoassay.

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