Selective Immobilization of Protein Clusters on Polymeric Nanocraters (pages 1242–1246)
A. Valsesia, P. Colpo, T. Meziani, F. Bretagnol, M. Lejeune, F. Rossi, A. Bouma and M. Garcia-Parajo
Version of Record online: 4 MAY 2006 | DOI: 10.1002/adfm.200500653
Chemically nanopatterned surfaces can be fabricated using a method based on colloidal lithography. Nanocraters of poly(acrylic acid) (carboxylic functionalized) surrounded by a matrix of poly(ethylene glycol) have been fabricated (see figure). The carboxylic groups of the craters are activated in order to induce covalent binding of fluorescent-labeled proteins.