Living Yeast Cells as a Controllable Biosynthesizer for Fluorescent Quantum Dots (pages 2359–2364)
Ran Cui, Hui-Hui Liu, Hai-Yan Xie, Zhi-Ling Zhang, Yi-Ran Yang, Dai-Wen Pang, Zhi-Xiong Xie, Bei-Bei Chen, Bin Hu and Ping Shen
Article first published online: 12 JUN 2009 | DOI: 10.1002/adfm.200801492
An example of how to solve seemingly intractable chemistry problems through biology by a novel strategy of coupling intracellular, unrelated biochemical reactions for controllable synthesis of CdSe QDs using living yeast cells as a biosynthesizer is demonstrated. The CdSe QDs can be tunably synthesized under in vivo conditions and at only 30 °C, instead of at high temperatures around 300 °C and using combustible, explosive, and toxic organic reagents.