Biofabricating Multifunctional Soft Matter with Enzymes and Stimuli-Responsive Materials (pages 3004–3012)
Yi Liu, Jessica L. Terrell, Chen-Yu Tsao, Hsuan-Chen Wu, Vishal Javvaji, Eunkyoung Kim, Yi Cheng, Yifeng Wang, Rein V. Ulijn, Srinivasa R. Raghavan, Gary W. Rubloff, William E. Bentley and Gregory F. Payne
Version of Record online: 19 APR 2012 | DOI: 10.1002/adfm.201200095
A multifunctional matrix is biofabricated by coupling self-assembly with enzymatic assembly. Self-assembly is triggered using stimuli-responsive materials and device-imposed electrical signals to electrodeposit a gelatin matrix. Enzymatic reactions serve to crosslink the gelatin and conjugate proteins to this matrix. These studies demonstrate the potential for enlisting biological materials and mechanisms to construct multifunctional soft matter.