Interactions Between Amino Acid-Tagged Naphthalenediimide and Single Walled Carbon Nanotubes for the Design and Construction of New Bioimaging Probes (pages 503–518)
Zhiyuan Hu, G. Dan Pantoş, Navaratnarajah Kuganathan, Rory L. Arrowsmith, Robert M. J. Jacobs, Gabriele Kociok-Köhn, Justin O'Byrne, Kerstin Jurkschat, Pierre Burgos, Rex M. Tyrrell, Stan W. Botchway, Jeremy K. M. Sanders and Sofia I. Pascu
Article first published online: 8 DEC 2011 | DOI: 10.1002/adfm.201101932
The recognition and coating of single-walled carbon nanotubes (SWNTs) by an amino acid-derivatized naphthalenedi-imide, NDI, is demonstrated using circular dichroism, UV–vis, and fluorescence spectroscopies and probed in the solid state by high-resolution transmission electron microscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy, and atomic force microscopy. The translocation in cancerous and healthy cells of the resulting fluorescence NDI@SWNT nanohybrid can be imaged by laser scanning confocal microscopies and its integrity in vitro is probed by fluorescence lifetime imaging (FLIM) techniques.