Metabolizable Bi2Se3 Nanoplates: Biodistribution, Toxicity, and Uses for Cancer Radiation Therapy and Imaging (pages 1718–1729)
Xiao-Dong Zhang, Jie Chen, Yuho Min, Gyeong Bae Park, Xiu Shen, Sha-Sha Song, Yuan-Ming Sun, Hao Wang, Wei Long, Jianping Xie, Kai Gao, Lianfeng Zhang, Saijun Fan, Feiyue Fan and Unyong Jeong
Article first published online: 27 NOV 2013 | DOI: 10.1002/adfm.201302312
The Bi2Se3 nanoplates for cancer radiation therapy are designed. 50 nm PVP-protected Bi2Se3 nanoplates induce long blood circulation. The Bi2Se3 nanoplates are metabolizable and show low in vivo toxicity. The tumor accumulation of the Bi2Se3 nanoplates exhibit strong enhancement of cancer radiotherapy.