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Keywords:

  • gold;
  • porous silicon;
  • nanoassembly;
  • thermal therapy;
  • hollow nanoshells
Thumbnail image of graphical abstract

Hollow gold nanoshells are more efficient in heat generation triggered by near infrared laser when they are loaded into porous silicon particles, which results in effective cancer-cell killing in vitro and in vivo. Collective electromagnetic coupling of nanoconfined hollow gold nanoshells leads to dramatic enhancement of thermal ablation.