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Communication

Magnetic Nanocomposite Sol–Gel Systems for Remote Controlled Drug Release

  1. Ashley M. Hawkins1,
  2. Chelsie E. Bottom1,
  3. Zhi Liang1,
  4. David A. Puleo2,
  5. J. Zach Hilt1,*

Article first published online: 9 DEC 2011

DOI: 10.1002/adhm.201100013

Issue

Advanced Healthcare Materials

Advanced Healthcare Materials

Volume 1, Issue 1, pages 96–100, January 11, 2012

Additional Information

How to Cite

Hawkins, A. M., Bottom, C. E., Liang, Z., Puleo, D. A. and Hilt, J. Z. (2012), Magnetic Nanocomposite Sol–Gel Systems for Remote Controlled Drug Release. Advanced Healthcare Materials, 1: 96–100. doi: 10.1002/adhm.201100013

Author Information

  1. 1

    Department of Chemical and Materials Engineering, University of Kentucky, 177 F. Paul Anderson Tower, Lexington, KY 40506-0046, USA

  2. 2

    Center for Biomedical Engineering, Unviersity of Kentucky, Lexington, KY 40506-0070, USA

*Department of Chemical and Materials Engineering, University of Kentucky, 177 F. Paul Anderson Tower, Lexington, KY 40506-0046, USA.

Publication History

  1. Issue published online: 3 JAN 2012
  2. Article first published online: 9 DEC 2011
  3. Manuscript Received: 27 OCT 2011

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Keywords:

  • remote drug release;
  • drug delivery;
  • iron oxide nanoparticles;
  • alternating magnetic field
Thumbnail image of graphical abstract

The remote heating of iron oxide nanoparticles in an alternating magnetic field is used to drive a thermoresponsive sol-gel block copolymer, Pluronic® F-127, through the upper phase transition temperature. This phase change triggers an accelerated release rate of a model drug. Actuation and return to baseline levels are demonstrated for multiple AMF doses.

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