Get access

Enhanced Enzymatic Thermal Stability and Activity in Functionalized Mesoporous Silica Monitored by 31P NMR

Authors


Abstract

original image

Organophosphorus hydrolase (OPH) is immobilized on ammonium-modified mesoporous silica particles. Thermal stability and activity are measured with a 31P NMR assay of the conversion of paraoxon (toxic) to its non-toxic hydrolysisproduct. After immobilization, OPH is significantly more active at room temperature and retained activity even after being heated to 45 °C for 1 month.

Get access to the full text of this article

Ancillary