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Keywords:

  • drug delivery;
  • colloids;
  • fluorescence microscopy;
  • mesoporous silica;
  • host-guest systems;
  • photosensitizer
Thumbnail image of graphical abstract

Different bioactive molecules are released into living cells from lipid-covered mesoporous silica nanoparticles. The release is triggered by light, as the particles feature covalently attached photosensitizers as membrane-opening agents. It is demonstrated that the particles achieve endosomal escape and that they release their cargo into the cytosol.