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Keywords:

  • microfluidics;
  • vascular;
  • 3D;
  • resistance;
  • microfiber
Thumbnail image of graphical abstract

A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels.