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Microfabrication-Compatible Nanoporous Gold Foams as Biomaterials for Drug Delivery

Authors

  • Erkin Seker,

    Corresponding author
    1. Department of Electrical and Computer Engineering, University of California, Davis, Davis, CA 95616, USA
    2. Center for Engineering in Medicine, Harvard Medical School & Massachusetts General Hospital, Shriners Hospitals for Children, Boston, MA 02114, USA
    • Department of Electrical and Computer Engineering, University of California, Davis, Davis, CA 95616, USA.
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  • Yevgeny Berdichevsky,

    1. Department of Neurology, Harvard Medical School & Massachusetts General Hospital, Boston, MA 02114, USA
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  • Kevin J. Staley,

    1. Department of Neurology, Harvard Medical School & Massachusetts General Hospital, Boston, MA 02114, USA
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  • Martin L. Yarmush

    1. Center for Engineering in Medicine, Harvard Medical School & Massachusetts General Hospital, Shriners Hospitals for Children, Boston, MA 02114, USA
    2. Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854, USA
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Abstract

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Nanoporous gold is a promising material for multi-functional bio-interfaces with its well-characterized surface chemistry, compatibility with conventional micropatterning techniques, electrical conductivity, and high effective surface-area for molecular release. This paper demonstrates its biocompatibility and capability for drug release to modulate cellular response.

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