Surface-Adhered Composite Poly(Vinyl Alcohol) Physical Hydrogels: Polymersome-Aided Delivery of Therapeutic Small Molecules



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The polymersome-aided trapping of a small antitumor compound in a poly(vinyl alcohol) hydrogel matrix and the subsequent viability of myoblasts adhering to this coating is reported. The results reveal an enhanced reduction of the cell viability when the therapeutic compound is delivered from the surface in comparison to solution-based delivery.