SEARCH

SEARCH BY CITATION

Keywords:

  • DNA;
  • drug delivery;
  • nanomedicine;
  • nanoparticles;
  • pH-responsive
Thumbnail image of graphical abstract

A novel drug nanocarrier that offers simple, direct, native form drug loading without involving any chemical modification and/or coupling step has been developed by using a pH-responsive DNA–gold nanoparticle conjugate. It can resist non-specific adsorption of serum proteins upon PEGylation and can provide efficient delivery and pH-triggered release of anticancer drugs to cancer cells, leading to high cytotoxicity.