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Hierarchical Structure of Electrospun Composite Fibers for Long-Term Controlled Drug Release Carriers

Authors

  • Changmin Hu,

    1. School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Hua Shan Road, Shanghai 200030, PR China
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  • Wenguo Cui

    Corresponding author
    1. School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Hua Shan Road, Shanghai 200030, PR China
    • School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Hua Shan Road, Shanghai 200030, PR China.
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Abstract

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A novel hierarchical structure of electrospun composite fibrous scaffolds is fabricated for long-term controlled drug release carriers. The low initial burst and long-term (more than 100 days) drug release of the composite fibrous scaffolds are due to the hierarchical structure and hydrophobicity of the composite fibers.

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