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Keywords:

  • nanotherapeutics;
  • drug and gene delivery;
  • cellular imaging;
  • supramolecular polymers;
  • quantum dots
Thumbnail image of graphical abstract

A novel multifunctional hybrid nanocarrier consisting of a red fluorescence quantum dot core and a star-shaped cationic β-cyclodextrin polymer shell is demonstrated. Chemotherapeutic drug paclitaxel is supramolecularly preloaded into the nanocarrier, which co-delivers the drug and DNA with an enhanced gene expression, while the quantum dot core allows simultaneous cellular imaging using laser scanning confocal microscopy.