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Mimicking the Biological Ligand–Receptor Principle for Universal Target Gene Delivery Mediated by Avidin–Biotin Interaction

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A facile and flexible targeting gene-delivery strategy is reported by mimicking the biological ligand–receptor principle based on avidin–biotin interaction. In vitro and in vivo investigations demonstrate that this strategy provides a simple, but universal alternative for potential target gene delivery as well as drug delivery.

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